Tổng quan thuốc chống đông đường uống thế hệ mới

Abstract

Vitamin K antogonist drug is used for patients with high risk of thrombosis, by preventing the blood clots that trigger heart attack and stroke, the anticoagulant drug warfarin, acenocoumarol saves countless lives. The anticoagulation drug is used after treating with heparin. Doctors must regularly monitor patients’ blood levels in order to prescribe a high enough dose of warfarin to prevent deadly blood clots, but not an excessive dose that could lead to fatal hemorrhage. Recently, new antithrombotic drugs that act directly by inhibiting activated coagulation factors such as factor X or thrombin have been developed and investigated in phase III clinical trials to offer the prevention and treatment venous thromboembolism and anticoagulant therapy management will be most probably improved in the coming years.